June 19, 2021 Learn about the differences between Vicodin and Percocet for pain reduction. If you are suffering from a severe injury, these two drugs can help.

Vicodin vs Percocet for Pain Reduction

Vicodin vs Percocet

Vicodin and Percocet are two potent prescription medication used to treat moderate to severe pain in adults and children. Vicodin is a brilliant combination of hydrocodone and acetaminophen (commonly known as paracetamol) and is a controlled substance in the United States. Here hydrocodone is an opioid pain reliever, and paracetamol is a non-opioid pain reliever. One can easily buy Vicodin online or other offlines mediums with and without prescription; however, it is better to purchase it against a legitimate prescription. It can induce severe side effects if not taken, keeping in mind some precautions and following the correct usage directions. It works by binding the opioid receptors present in the central nervous system and provides relief from pain.Hydrocodone/acetaminophen is also a common drug of abuse, and that is why its distribution is limited.

One the other hand, there is Percocet, which is the combination of oxycodone and paracetamol. This drug is too a controlled substance in the United States. Acetaminophen is a generic Tylenol, sometimes called APAP, so the combination medication might also get into the market as oxycodone/APAP. One suffering from acute pain can buy Percocet online without much difficulty to get treat pain for a short period. Purchasing this drug against a valid prescription is wise advice to follow to avoid any misuse and after effects of this pain reliever. It works by interacting with specific opioid receptors, overpowering pain, and generating a feeling of euphoria and relaxation. Percocet is also habit-forming, and users can quickly become addicted to it.


It is extremely crucial to use these medicines accurately as any mistake while consuming can prove lethal for patients suffering from chronic pain. Talking with your doctor about the correct way to inject or consume these opioids is always beneficial. Moreover, you can also look for help in the patient’s guide provided at the time of purchasing the packs of the drugs.

Measuring the correct quantity of theses pain killers using special containers or spoon provided with the pack is the way to go; you must not use any utensils other than those marked with limits. The dosage should not exceed the maximum permissible limit for Vicodin as well as Percocet. These medications work best when taken as soon as pain symptoms start to show up in the body; waiting longer will not do any good for you.

Forms and Dosage

Both of these medications come in brand names and generic versions, so that one can take them orally and in tablet form to ease the process of consumption. It depends wholly on the user which form they prefer and can buy them online or from physical pharmacies.


  • Vicodin Tablets: The prescribed dose of this drug in the tablet form is 300 mg of acetaminophen (paracetamol) combined with 5 mg or 7.5 mg or 10 mg of hydrocodone to get relief from acute pain for some time. Consult your doctor for further plans, according to the effects of the initial dose.
  • Generic tablets: Dosage of the generic tablet form of this drug is 300 mg to 325 mg of acetaminophen in combination with 2.5 mg,5 mg,7 mg, or 10 mg of hydrocodone.
  • Generic Liquid: Dosage of this drug’s oral liquid form is 325 mg of acetaminophen combined with 7.5 mg or 10 mg( only if advised) of hydrocodone per 15 ml.
  • One should consume Vicodin every 4 – 6 hours for significant pain reduction.


  • Percocet Tablet: The dosage of this drug’s tablet form is 325 mg acetaminophen combined with 2.5mg,5mg,7mg, or 10 mg of oxycodone.
  • Generic Tablets: The dosage of this drug’s generic tablet form is 300 mg to 325 mg of acetaminophen combined with 2.5 mg,6 mg,7 mg, or 10 mg of oxycodone.
  • Generic Liquid: The dosage of this drug’s oral liquid form is 325 mg of acetaminophen combined with 5 mg of oxycodone every 5 ml.
  • One should take Percocet every 4 – 6 hours for significant pain reduction.


Both Vicodin and Percocet are effective in treating pain due to various terrible illnesses. Multiple studies conducted to demonstrate their effectiveness in providing relief from moderate to severe pain were satisfactory. Both of these drugs were able to overpower the preception of feeling pain after interacting with the brain and the central nervous system.

Both these opioids help lower pain from fractures and painful illnesses like cancer, frozen shoulders, slipped disc, cluster headaches, and several injury pains upto a significant extent. Although most studies agree, both Vicodin and Percocet are equally competent in treating chronic pain. Some latest studies contradict this and claim that oxycodone present in Percocet is 1.5 times more potent than hydrocodone, the drug present in Vicodin if taken in equal doses for a period.

Side effects

There are specific side effects attached to both pain-relieving drugs one should keep in mind before opting for these potent drugs. Consulting your doctor before you reach out to buy Vicodin online is something you must think about to avoid this drug’s side effects. However, it is nearly impossible to get all of the impacts simultaneously in an individual. Most of them are manageable, but getting an overview of the aftereffects must be in your priority list in advance.

Similar is the case with Percocet, where some of the side effects can get out of hand anytime, it is always advisable to get in touch with your doctor before consuming this effective but powerful drug. You must go through all the aftermaths possible from the drugs in patients before you buy Percocet online or through other legitimate means.

Interestingly, both of these opioid medications share side effects that show up in these medication’s consumers. Both drugs can cause constipation and even affect mental and physical abilities like weakening judgment and reflexes; this usually happens in overdoses of these drugs and can even prove fatal in sensitive cases.

Common side effects

  • Vomiting
  • Headache
  • Constipation
  • Nausea
  • Mood swings
  • Anxiety and depression
  • Drowsiness
  • Dizziness
  • Difficulty in breathing
  • Dry mouth
  • Poor coordination
  • Impaired reflexes

Severe side effects

  • Dysphoria
  • Painful urination
  • Allergic reaction
  • Itching
  • Trouble breathing
  • Swelling of tongue and throat
  • Rapid heartbeat
  • Low blood pressure
  • Seizures
  • Skin rashes

Interactions and Warnings


Vicodin and Percocet are potent drugs that can also react with other medications and may show some severe impacts that you must be aware of before committing to these pain relief medicines. Vicodin reacts with a total of 565 drugs in which 199 combinations can cause significant reactions. It can respond acebutolol, aldesleukin, alfuzosin, amiloride, to name a few. Similarly, Percocet interacts with a total of 551 other drugs, which includes aspirin, gabapentin, methadone, naproxen, tramadol,xanax any many more, so you must get a clear understanding of the medicine and talk with your doctor.


  • You must not hesitate to talk with your doctor if you have any allergies from prescribed drugs or constituents of these two drugs; these drugs might contain some inactive ingredients that can cause serious after effects.
  • You must tell your doctor if you come with any family history of brain disorders or respiratory issues or breathing problems, or substance use disorders. These can disrupt the situation if taken with these potent medicines.
  • Both these drugs can cause drowsiness and dizziness after consumption, so you must avoid driving or using dangerous machinery within a few hours of taking the pills.

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